Abdominal Visceral Adiposity in the First Trimester Predicts Glucose Intolerance in Later Pregnancy  

Oleh:

Martin, Aisling Mary ; Berger, Howard ; Nisenbaum, Rosane ; Lausman, Andrea Y.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 32 no. 07 (Jul. 2009), page 1308-1310.
Topik: Abdominal Visceral Adiposity; First Trimester; Glucose Intolerance; Later Pregnancy

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K.2009.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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OBJECTIVE : To assess whether abdominal adiposity in early pregnancy is associated with a higher risk of glucose intolerance at a later gestational stage. RESEARCH DESIGN AND METHODS : Subcutaneous and visceral fat was measured with ultrasonography at ~12 weeks' gestation. A 50-g glucose challenge test (GCT) was performed between 24 and 28 weeks' gestation. The risk of having a positive GCT (=7.8 mmol/l) was determined in association with subcutaneous and visceral adipose tissue depths above their respective upper-quartile values relative to their bottom three quartile values. RESULTS : Sixty-two women underwent GCTs. A visceral adipose tissue depth above the upper quartile value was significantly associated with a positive GCT in later pregnancy (adjusted odds ratio 16.9 [95% CI 1.5–194.6]). No associations were seen for subcutaneous adipose tissue. CONCLUSIONS : Measurement of visceral adipose tissue depth in early pregnancy may be associated with glucose intolerance later in pregnancy.

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