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ArtikelVitamin B12, Folate, Homocysteine and Urinary Methylmalonic Acid Levels in Infants  
Oleh: Karademir, F. ; Suleymanoglu, S. ; Ersen, A. ; Aydinoz, S.
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Journal of International Medical Research vol. 35 no. 03 (May 2007), page 384-388.
Topik: Vitamin B12; folate; homocysteine; urinary methylmalonic acid levels; infants
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: J11.K.2007.01
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
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Isi artikelSerum vitamin B12 and folate, and their functional markers, plasma homocysteine and urinary methylmalonate (uMMA) were measured in 204 healthy, term infants at birth, and at 2 and 6 months. Compared with infants receiving formula food, those fed mother’s milk had lower vitamin B12 and folate at 2 and 6 months. In infants receiving mother’s milk, vitamin B12 levels were similar at birth (238 pg/ml) and 2 months (243 pg/ml), whereas with formula milk the level was significantly higher at 2 months (558 pg/ml) than at birth (257 pg/ml). Vitamin B12 was negatively correlated with homocysteine at birth and 6 months. The level of uMMA (mmol/mol creatinine) was higher at 2 (mother’s milk, 25.5; formula, 23.97) and 6 months (19.77; 15) than at birth (11.97; 10.88), and was not correlated with vitamin B12 levels. Homocysteine may be a reliable marker of vitamin B12 status in neonates and infants; however, uMMA is not suitable as a marker of vitamin B12 status.
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