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Vitamin B12, Folate, Homocysteine and Urinary Methylmalonic Acid Levels in Infants
Oleh:
Karademir, F.
;
Suleymanoglu, S.
;
Ersen, A.
;
Aydinoz, S.
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The Journal of International Medical Research vol. 35 no. 03 (May 2007)
,
page 384-388.
Topik:
Vitamin B12
;
folate
;
homocysteine
;
urinary methylmalonic acid levels
;
infants
Ketersediaan
Perpustakaan FK
Nomor Panggil:
J11.K.2007.01
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Serum vitamin B12 and folate, and their functional markers, plasma homocysteine and urinary methylmalonate (uMMA) were measured in 204 healthy, term infants at birth, and at 2 and 6 months. Compared with infants receiving formula food, those fed mother’s milk had lower vitamin B12 and folate at 2 and 6 months. In infants receiving mother’s milk, vitamin B12 levels were similar at birth (238 pg/ml) and 2 months (243 pg/ml), whereas with formula milk the level was significantly higher at 2 months (558 pg/ml) than at birth (257 pg/ml). Vitamin B12 was negatively correlated with homocysteine at birth and 6 months. The level of uMMA (mmol/mol creatinine) was higher at 2 (mother’s milk, 25.5; formula, 23.97) and 6 months (19.77; 15) than at birth (11.97; 10.88), and was not correlated with vitamin B12 levels. Homocysteine may be a reliable marker of vitamin B12 status in neonates and infants; however, uMMA is not suitable as a marker of vitamin B12 status.
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