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Apri index changes after 4 weeks treatment of pentoxyfylline in chronic hepatitis B
Oleh:
Zain, Lukman Hakim
;
Zulfan
Jenis:
Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi:
Jurnal Kedokteran YARSI vol. 16 no. 02 (May 2008)
,
page 83-86.
Topik:
Liver Fibrosis
;
Hepatic Stellate Cell
;
Pentoxifylline
;
APRI Index
Ketersediaan
Perpustakaan PKPM
Nomor Panggil:
J51
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Perpustakaan FK
Nomor Panggil:
J26.K
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Nowadays studies have shown that liver fibrosis is a reversible process. Theraupetic target on hepatic stellate cell (HSC) through inhibition of fibrotic signaling transduction is one of the way to treat liver fibrosis (e.g. pentoxifylline). APRI index, one of the indirect marker of liver fibrosis, had shown significant correlation (Spearman correlation y=0.7) with liver fibrosis degree in hepatitis B and C. This study was aimed to evaluated the effect of pentoxifylline treatment in 4 weeks for liver fibrosis measured by APRI index.
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