Discrete-Event Simulation Models Of Plasmodium Falciparum Malaria  

Oleh:

McKenzie, F. Ellis ; Wong, Roger C. ; Bossert, William H.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Simulation vol. 71 no. 4 (Apr. 1995), page 250-261.
Topik: Epidemiology; infectious disease; malaria; population biology; prevalence; transmission; vector
Fulltext: 250.pdf (1.12MB)

Isi artikel

We develop discrete-event simulation models using a single "timeline" variable to represent the Plasmodium falciparum lifecycle in individual hosts and vectors within interacting host and vector populations. Where they are comparable, our conclusions regarding the relative importance of vector mortality and the durations of host immunity and parasite development are congruent with those of classic differential-equation models of malaria epidemiology. However, our results also imply that in regions with intense perennial transmission, the influence of mosquito mortality on malaria prevalence in humans may be rivaled by that of the duration of host infectivity.

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