Reversing Atherosclerosis?  

Oleh:

Curtiss, Linda K.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 360 no. 11 (Mar. 2009), page 1144.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2009.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Atherosclerosis is reversible and involves the removal of trapped cholesterol-loaded foam-cell macrophages from the arterial intima. A recent study by Park and colleagues1 showed that these foam cells are trapped by interaction with oxidized low-density lipoprotein (LDL) and can be remobilized by dynamic exposure to key antioxidants such as resveratrol, a polyphenolic compound found in grapes and red wine and having potential antiatherogenic properties.2 It was once thought that atherosclerosis was a lipid-storage disease and that its pathology — a lesion or plaque causing arterial obstruction — resulted from the accumulation of lipid within arteries. It is now understood that . . .

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