Detail RESEARCH NOTE: Antibacterial Activity of Panduratin A and Isopanduratin A Isolated from Kaempferia pandurata Roxb. against Acne-causing Microorganisms (in Food Sci. Biotechnol. Vol. 17, No. 6) Bibliografi Author: Shim, Jae-Seok ; Hwang, Jae-Kwan ; Gwon, Song-Hui ; Song, Min-Soo ; Lee, Chan-Woo ; Kim, Han-Sung Topik: Antibacterial; Panduratin A; Isopanduratin A; Kaempferia pandurata Roxb.; Propionibacterium acnes; Skin Disease Microorganism Bahasa: (EN )    Edisi: Apr 2008     Penerbit: Korea Institute of Science and Technology Information     Tempat Terbit: Seoul    Tahun Terbit: 2008     Jenis: Article - diterbitkan di jurnal ilmiah internasional Fulltext: 17.6(41)-2008-04-022.pdf (607.73KB; 1 download) Abstract Propionibacterium acnes is the predominant organism in sebaceous regions of the skin and is thought to play an important role in the pathogenesis of inflamed lesions. Antibacterial compounds against P. acnes were isolated from the ethanol extract of Kaempferia pandurata Roxb. and identified as panduratin A and isopanduratin A. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of panduratin A for P. acnes were 2 and 4 µg/mL, respectively, while those of isopanduratin A were 4 and 8 µg/mL, respectively. The time-dependent killing effect showed that panduratin A and isopanduratin A completely inhibited the growth of P. acnes at 4 and 8 µg/mL in 48 hr, respectively. Panduratin A and isopanduratin A demonstrated high antibacterial activities not only against P. acnes but also other skin microorganisms. The results suggest that panduratin A and isopanduratin A could be employed as natural antibacterial agents to inhibit the growth of acne and skin disease causing microorganisms. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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