Detail Inhibition of bacterial quorum sensing by vanilla extract (in Letters in Applied Microbiology 42) Bibliografi Author: Hwang, Jae-Kwan ; Rukayadi, Y. ; Choo, J.H. Topik: Chromobacterium violaceum CV026; N-hexanoyl homoserine lactone; Quorum Sensing; Vanilla; Violacein Bahasa: (EN )    Edisi: Oct 2005     Penerbit: Society for Applied Microbiology     Tempat Terbit: Bedford    Tahun Terbit: 2006     Jenis: Article - diterbitkan di jurnal ilmiah internasional Fulltext: 3. Inhibition of bacterial quorum sensing by vanilla extract..pdf (116.03KB; 11 download) Abstract Aims: The purpose of this study was to search for a novel quorum sensing inhibitor and analyse its inhibitory activity. Methods and Results: Quorum sensing inhibition was monitored using the Tn-5 mutant, Chromobacterium violaceum CV026. Vanilla beans (Vanilla planifolia Andrews) were extracted using 75% (v/v) aqueous methanol and added to C. violaceum CV026 cultures. Inhibitory activity was measured by quantifying violacein production using a spectrophotometer. The results have revealed that vanilla extract significantly reduced violacein production in a concentrationdependent manner, indicating inhibition of quorum sensing. Conclusions: Vanilla, a widely used spice and flavour, can inhibit bacterial quorum sensing. Significance and Impact of the Study: The results suggest that the intake of vanilla-containing food materials might promote human health by inhibiting quorum sensing and preventing bacterial pathogenesis. Further studies are required to isolate specific substances from vanilla extract acting as quorum sensing inhibitors. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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