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Initial validation of a screening battery for the detection of HIV associated cognitive impairment (in The Clinical Neuropsychologist Vol 18 No 2)
Bibliografi
Author:
Carey, Catherine L.
;
Woods, Steven Paul
;
Rippeth, Julie D.
;
Gonzalez, Raul
;
Marcott, Thomas D.
;
Moore, David J.
;
Grant, Igor
;
Heaton, Robert K.
;
Group, HNRC
Topik:
Detecting HIV related neuropsychoiogical (NP) impairment
Bahasa:
(EN )
Penerbit:
Psychology Press
Tempat Terbit:
Hove, East Sussex
Tahun Terbit:
2004
Jenis:
Article - diterbitkan di jurnal ilmiah internasional
Fulltext:
Initial Validation of a Screening Battery.pdf
(3.89MB;
1 download
)
Abstract
This study sought lo develop and validate a screening battery for deteeting HIV related
neuropsychoiogical (NP) impairment. Six NP measures representing the ability areas most likely
affected by HIV infection were paired in 14 combinations and their diagnostic accuracy rates compared. The measures were selected from a larger NP battery administered to 190 HIV-seropositive {H1V+) participants. Screening battery performance was classified as NP impaired if demographically corrected T-scores fell below 40 on both tests, or below 35 on one test. Using blind clinical ratingsof NP test results from the largerbattery as the "gold standard" for global NP status (impaired or unimpaired), we found that several test combinations demonstrated adequate diagnostic accuracy in detecting NP impairment. Ihe most sensitive test combinations were the Hopkitis Verbal Lx-arning Test - Revised (HVLT-R; Total Recall) and the Grooved PegboardTesttiondominant hand(PND) pair and the HVLT-R and WAIS-III Digit Symbol (DS) subtest pair (sensitivity = 78% and 75%, respectively). Both test combinations (HVLT-R/PND. HVLT-R/DS) were more accurate than
the HIV Dementia Scale (HDS) in classifying HIV+ participants as NP impaired or unimpaired. Results suggest that demographically corrected '/"-scores from pairs of common NP measures may serve as valid screening instruments to identify subjects with HIV-related neurocognitive impairment who could benefit from more extensive NP examination.
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