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Anti-biofilm Activity of Xanthorrhizol Isolated from Curcuma xanthorrhiza Roxb. against Bacterial Biofilms Formed by Saliva and Artificial Multi-species Oral Strains (Food Science and Biotechnology, Vol. 18 No. 2, 2009 p.556-560)
Bibliografi
Author:
Yanti
;
Rukayadi, Yaya
;
Lee, Kwanhyoung
;
Han, Sunghwa
;
Hwang, Jae-Kwan
Topik:
Anti-Biofilm Activity
;
Curcuma Xanthorrhiza Roxb.
;
Xanthorrhizol
;
Oral Biofilm
;
JABFUNG-YANTI-2018-00
Bahasa:
(EN )
Penerbit:
The Korean Society of Food Science and Technology
Tempat Terbit:
Seoul
Tahun Terbit:
2009
Jenis:
Article - diterbitkan di jurnal ilmiah internasional
Fulltext:
Anti-biofilm Activity of Xanthorrhizol Isolated from Curcuma Xanthorrhiza Roxb.pdf
(2.34MB;
6 download
)
2009_FSB_XANTHO_BIOFILM.pdf
(856.01KB;
2 download
)
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Abstract
Xanthorrhizol. a sesquiterpene isolated from Curcuma xanthorrhiza Roxb., was used to investigate its effect on reducing the saliva and multi-species oral biofilms consisting of Streptococcus mutans. Streptococcus sanguis, and Actinomyces viscosus by anti-biofilm and confocal laser scanning microscopy (CLSM) assays. Xanthorrhizol exhibited significant anti-biofilm activity in the dose- and time-dependent manners. Exposure to 2 and 5 µg/mL xanthorrhizol for 30 min remained <50% of saliva and multi-species biofilms formed for 24 hr. In addition, exposure to 10 µg/mL xanthorrhizol for 30 min reduced 65 and 77% of 24 hr saliva and multi-species oral biofilms. respectively. CLSM results visually demonstrated that xanthorrhizol reduced bacterial viability in the saliva and multi-species oral biofilms. These results suggest that C. xanthorrhiza Roxb. containing xanthorrhizol with strong anti-biofilm activity can be employed as a plant source for oral care functional foods.
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