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BukuAnti-biofilm Activity of Xanthorrhizol Isolated from Curcuma xanthorrhiza Roxb. against Bacterial Biofilms Formed by Saliva and Artificial Multi-species Oral Strains (Food Science and Biotechnology, Vol. 18 No. 2, 2009 p.556-560)
Bibliografi
Author: Yanti ; Rukayadi, Yaya ; Lee, Kwanhyoung ; Han, Sunghwa ; Hwang, Jae-Kwan
Topik: Anti-Biofilm Activity; Curcuma Xanthorrhiza Roxb.; Xanthorrhizol; Oral Biofilm; JABFUNG-YANTI-2018-00
Bahasa: (EN )    
Penerbit: The Korean Society of Food Science and Technology     Tempat Terbit: Seoul    Tahun Terbit: 2009    
Jenis: Article - diterbitkan di jurnal ilmiah internasional
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Abstract
Xanthorrhizol. a sesquiterpene isolated from Curcuma xanthorrhiza Roxb., was used to investigate its effect on reducing the saliva and multi-species oral biofilms consisting of Streptococcus mutans. Streptococcus sanguis, and Actinomyces viscosus by anti-biofilm and confocal laser scanning microscopy (CLSM) assays. Xanthorrhizol exhibited significant anti-biofilm activity in the dose- and time-dependent manners. Exposure to 2 and 5 µg/mL xanthorrhizol for 30 min remained <50% of saliva and multi-species biofilms formed for 24 hr. In addition, exposure to 10 µg/mL xanthorrhizol for 30 min reduced 65 and 77% of 24 hr saliva and multi-species oral biofilms. respectively. CLSM results visually demonstrated that xanthorrhizol reduced bacterial viability in the saliva and multi-species oral biofilms. These results suggest that C. xanthorrhiza Roxb. containing xanthorrhizol with strong anti-biofilm activity can be employed as a plant source for oral care functional foods.
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