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DNA microarray analysis of brain cancer: molecular classification for therapy (in Nature Reviews Neuroscience 5)
Bibliografi
Author:
Mischel, Paul S.
;
Cloughesy, Timothy F.
;
Nelson, Stanley F.
Topik:
DNA Microarray
;
Brain Cancer
Bahasa:
(EN )
Edisi:
OCT 2004
Penerbit:
Nature Publishing Group
Tempat Terbit:
New York
Tahun Terbit:
2004
Jenis:
Article - diterbitkan di jurnal ilmiah internasional
Fulltext:
review-brain-tumor-class.pdf
(336.32KB;
1 download
)
Abstract
Primary brain tumours are among the most lethal of all cancers, largely as a result of their lack of responsiveness to current therapy. Numerous new therapies hold great promise for the treatment of patients with brain cancer, but the main challenge is to determine which treatment is most likely to benefit an individual patient. DNA-microarray-based technologies, which allow simultaneous analysis of expression of thousands of genes, have already begun to uncover previously unrecognized patient subsets that differ in their survival. Here, we review the progress made so far in using DNA microarrays to optimize brain cancer therapy.
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