Detail Antibacterial Activity of Marine Bacteria Associated with Sponge Aaptos Sp. Against Multi Drugs Resistant (MDR) Strains (Jurnal Matematika dan Sains, Vol. 12 No. 4 Desember 2007) Bibliografi Author: Hutagalung, Rory Anthony ; Lestari, Endang Sri ; Sabdono, Agus ; Radjasa, Ocky Karna ; Kencana, Duhita Sinidhikaraning Topik: Antibacterial; Marine bacteria; Sponge Aaptos sp.; MDR Bahasa: (EN )     Penerbit: [s.n]     Tempat Terbit: Jakarta    Tahun Terbit: 2007     Jenis: Article - diterbitkan di jurnal ilmiah nasional Fulltext: Antibacterial Activity of Marine Bacteria Associated with sponge Aaptos sp.pdf (207.23KB; 1 download) Abstract The improper and uncontrolled uses of antibiotics against pathogenic bacteria have resulted in the occurrence of Multi Drugs Resistant (MDR) strains. There is now an urgency to find alternative antibiotics to combat the MDR strains. Sponge associated microorganisms are among the most interesting and promising marine natural product sources which produce polyketide and non ribosomal peptide products with various biological activities. In this study, marine bacteria were isolated from sponge Aaptos sp. collected from North Java Sea, and were screened for antibacterial activity against MDR strains. Three out of 64 bacterial isolates were successfully screened and were found to be active against MDR strains, in which two isolates (SPA1 and SPA5) were active against resistant strain Escherichia coli and one isolate (SPA21) against resistant strain Proteus sp., respectively. These active isolates were also capable of amplifying NRPS (Non Ribosomal Peptide Synthetases) gene fragments necessary for the biosynthesis of non ribosomal peptides. The molecular identification based on partial 16S DNA nukleotide sequences indicates that the active isolates are Halomonas aquamarina, Alpha proteobacterium, and Pseudoalteromonas luteviolacea. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

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