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BukuDNA Microarray Analysis of Complex Biologic Processes (in J Am Soc Nephrol 12)
Bibliografi
Author: Kurella, Manjula ; Hsiao, Li-Li ; Yoshida, Takumi ; Randall, Jeffrey D. ; Chow, Gary ; Sarang, Satinder S. ; Jensen, Roderick V. ; Gullans, Steven R.
Topik: cDNA Microarray
Bahasa: (EN )    Edisi: 2001    
Penerbit: American Society of Nephrology     Tempat Terbit: Washington, DC    Tahun Terbit: 2001    
Jenis: Article - diterbitkan di jurnal ilmiah internasional
Fulltext: 1072.pdf (278.61KB; 0 download)
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Abstract
DNA microarrays, or gene chips, allow surveys of gene expression, (i.e., mRNA expression) in a highly parallel and comprehensive manner. The pattern of gene expression produced, known as the expression profile, depicts the subset of gene transcripts expressed in a cell or tissue. At its most fundamental level, the expression profile can address qualita-tively which genes are expressed in disease states. However, with the aid of bioinformatics tools such as cluster analysis, self-organizing maps, and principle component analysis, more DNA microarrays, or gene chips, allow surveys of gene expression, (i.e., mRNA expression) in a highly parallel and comprehensive manner. The pattern of gene expression produced, known as the expression profile, depicts the subset of gene transcripts expressed in a cell or tissue. At its most fundamental level, the expression profile can address qualita-tively which genes are expressed in disease states. However, with the aid of bioinformatics tools such as cluster analysis, self-organizing maps, and principle component analysis, more
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