Powerful and Cost-Efficient Designs for Longitudinal Intervention Studies With Two Treatment Groups  

Oleh:

Moerbeek, Mirjam

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Journal Of Educational And Behavioral Statistics vol. 33 no. 1 (Mar. 2008), page 41-61.
Topik: power; sample sizes; study duration; dropout; polynomial growth model
Fulltext: 41.pdf (487.14KB)

Isi artikel

Three issues need to be decided in the design stage of a longitudinal intervention study: the number of persons, the number of repeated measurements per person, and the duration of the study. The degree to which polynomial effects vary across persons and the drop-out pattern also influence the statistical power to detect intervention effects. This article presents a framework that allows researchers to calculate the power of a proposed design and compare alternative designs on the basis of their costs and sample sizes. A multilevel regression model with polynomial effects varying across persons is used to relate response to time. The persons’ length of stay in the study is modeled using a survival function.

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