The signal transduction pathways endothelin-3 induced vasorelaxation.  

Oleh:

Sudjarwo, Sri Agus

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Jurnal Kedokteran YARSI vol. 09 no. 02 (May 2001), page 086.
Topik: Endothelin-3; Endothelium-dependent Relaxation; Ca2+ Levels (cytosolic)

Ketersediaan

Perpustakaan PKPM Nomor Panggil: J51 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

In isolated rat aorta, endothelin (ET)-3 increased cytosolic Ca2+ ([Ca2+]i) in the endotheliun at a concentration (100nM) which had little effect on muscle resting tone. In the absence of external Ca2+, ET-3 still transiently increased endothelial [Ca2+]i, Verapamil (10uM) did not change the effects of ET-3. In aortas stimulated with 100nM norepinephrine, 100nM ET-3 relaxed the muscle with an increase in endothelial [Ca 2+]i.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali