Karakterisasi molekular fragmen gen mexB isolat pseudomonas aeruginosa multiresisten.  

Oleh:

Badaruddin, Fatmawaty ; Supardi, Imam ; Warsa, Usman Chatib ; Retnoningrum, Debbie Sofie

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Jurnal Kedokteran YARSI vol. 16 no. 01 (Jan. 2008), page 018.
Topik: Antibiotic Resistant; Efflux Pump; Sensitivity Test; Substrate Recognition Site

Ketersediaan

Perpustakaan PKPM Nomor Panggil: J51 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada	Lihat Detail Induk
Perpustakaan FK Nomor Panggil: J26.K.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada	Lihat Detail Induk

Isi artikel

Antibiotics have been widely used in the treatment of infectious diseases. However, their affectiveness has been questioned due to the tendency of some bacterial resistance to antibiotics. Pseudomonis aeruginosa among athers has been known to be resistant to several antibiotics due to its MexAB-OprM efflux pump. Perhaps, the nucleotide sequence of its mexB gene fragment has changed followed by change in amino acid sequence leading to alteration of the substrate recognition site.

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