Effect of omega 3 and omega 6 fatty acid intakes from diet and supplements on plasma fatty acid levels in the first 3 years of life  

Oleh:

Hoyos, Camilla ; Almqvist, Catarina ; Garden, Frances ; Wei, Xuan ; Oddy, Wendy

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Asia Pacific Journal of Clinical Nutrition (keterangan: ada di Proquest) vol. 17 no. 04 (2008), page 552.
Topik: omega–3 fatty acids; omega–6 fatty acids; dietary supplements; plasma; dietary intake

Ketersediaan

Perpustakaan FK Nomor Panggil: A27.K.2008.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Background: The optimal method for conducting omega (n–)3 polyunsaturated fatty acid (PUFA) supplementation trials in children is unknown. Aim: To assess the impact of n–3 and n–6 PUFA intake from the background diet on plasma levels of n–3 and n–6 PUFA in children aged 0-3 years, with and without n–3 supplementation. Methods: Subjects were randomised antenatally to receive either n–3 PUFA supplements and low n–6 PUFA cooking oils and spreads or a control intervention, designed to maintain usual fatty acid intake. Dietary intake was assessed at 18 months by 3–day weighed food record and at 3 years by food frequency questionnaire. Plasma phospholipids were measured at both time points. Associations were tested by regression. Results: N–3 PUFA intake from background diet did not significantly affect plasma n–3 levels. In contrast, n–6 PUFA intake in background diet was positively related to plasma n–6 levels in both study groups. In addition, n–6 PUFA intake from diet was negatively associated with plasma n–3 levels at 18 months and 3 years (–0.16%/g n–6 intake, 95%CI –0.29 to –0.03 and –0.05%/g n–6 intake, 95%CI –0.09 to –0.01, respectively) in the active group, but not in the control group. Conclusion: Interventions intending to increase plasma n–3 PUFA in children by n–3 supplementation should also minimise n–6 PUFA intake in the background diet.

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