Nuclear transfer to prevent mitochondrial DNA diseases  

Oleh:

Poulton, James L. ; Kennedy, S. ; Oakeshott, P ; John, J St

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Lancet (keterangan: ada di Proquest) vol. 368 no. 9538 (Sep. 2006), page 841.

Ketersediaan

Perpustakaan FK Nomor Panggil: L01.K.2006.05 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

In their Viewpoint (July 1, p 87), 1 D T Brown and colleagues discuss the use of somatic-cell nuclear and pronuclear transfer to alter the mitochondrial population of human embryos to prevent maternally inherited mitochondrial DNA disease. The transfer of an adult somatic cell nucleus into an enucleated recipient oocyte is how Dolly the sheep was created, which caused mitochondrial DNA inheritance from the recipient not the donor. But is “swapping” mitochondrial DNA a viable alternative to more co ...

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