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TLR Polymorphisms and the Risk of Invasive Fungal Infections
Oleh:
Pamer, Eric G.
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The New England Journal of Medicine (keterangan: ada di Proquest) vol. 359 no. 17 (Oct. 2008)
,
page 1836.
Ketersediaan
Perpustakaan FK
Nomor Panggil:
N08.K.2008.05
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Allogeneic hematopoietic stem-cell transplantation is a potentially lifesaving cancer therapy that, at least temporarily, renders patients highly immunocompromised and vulnerable to infection. Aspergillus fumigatus, a common environmental fungus that causes invasive infections in immunocompromised persons, is particularly problematic in patients who have undergone this treatment.1 Although the risk of the development of aspergillosis correlates with the degree of immunosuppression and the intensity of exposure to fungal spores, these factors alone do not explain why this infection develops in approximately 5 to 10% of patients who have received these transplants, whereas it does not develop in the remaining 90 to 95% . . .
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