FGF-23 and Outcomes Research — When Physiology Meets Epidemiology  

Oleh:

Chi-yuan Hsu

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 359 no. 06 (Aug. 2008), page 640.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2008.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

In this issue of the Journal, Gutiérrez and colleagues report the results of a study, conducted with an efficient nested case–cohort design, that showed that among patients who were beginning hemodialysis treatment, higher serum levels of fibroblast growth factor 23 (FGF-23) at the initiation of dialysis predicted 1-year mortality (odds ratio for the highest vs. lowest quartile, 5.7; 95% confidence interval, 2.6 to 12.6).1 This association was independent of serum phosphate levels and other confounders recorded in a clinical database. This article is of interest because it concerns a subject that is at the intersection of several important evolving areas. . . .

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