Chromosomal Abnormalities in Cancer  

Oleh:

Frohling, Stefan ; Dohner, Hartmut

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 359 no. 07 (Aug. 2008), page 722.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2008.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Cytogenetic abnormalities are a characteristic attribute of cancer cells. To date, clonal chromosome aberrations have been found in all major tumor types from more than 54,000 patients (http://cgap.nci.nih.gov/Chromosomes/Mitelman), and their identification continues as a result of technical improvements in conventional and molecular cytogenetics. The World Health Organization Classification of Tumours recognizes a growing number of such genetic changes and uses them to define specific disease entities. Many of these aberrations have emerged as prognostic and predictive markers in hematologic cancers and certain types of solid tumors. Furthermore, the molecular characterization of cytogenetic abnormalities has provided insights into the . . .

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