Neuroblastoma — Linking a Common Allele to a Rare Disease  

Oleh:

Kushner, Brian H. ; Nai-Kong, V. Cheung

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 358 no. 24 (Jun. 2008), page 2635.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2008.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Neuroblastoma has a notorious reputation among solid tumors of childhood because of its frequently massive and widespread tumor burden. Yet stage for stage, this embryonal neoplasm of the sympathetic nervous system has become the most curable of the common pediatric solid tumors.1 More than 90% of patients with localized neuroblastomas, including those with spread to the regional lymph nodes, will survive, often with little or no cytotoxic therapy. Rates of cure of metastatic neuroblastoma exceed 90% among infants (who are usually treated with low-dose chemotherapy) and are approximately 25% among toddlers; in contrast, osteomedullary metastases associated with other pediatric solid . . .

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