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Cognitive slowing in decision tasks in early and advanced parkinson's disease
Oleh:
Zimmermann, Peter
;
Sprengelmeyer, Reiner
;
Wallesch, Claus-W.
;
Fimm, Bruno
Jenis:
Article from Bulletin/Magazine
Dalam koleksi:
Brain and Cognition vol. 18 no. 1 (Jan. 1992)
,
page 60-69.
Ketersediaan
Perpustakaan PKBB
Nomor Panggil:
405/BAC/18
Non-tandon:
tidak ada
Tandon:
1
Lihat Detail Induk
Isi artikel
Ten untreated patients with recently diagnosed Parkinson's disease (PO), 9 treated patients with more advanced pathology, and 17 matched normal controls were investigated with three reaction tasks with increasing cognitive load but identical motor requirements: simple reaction, choice reaction with indicative stimuli, and choice reaction with ambiguous stimuli. Times required until a home key was released (= reaction time) and from then until a response key was pressed (= movement time) were recorded. Estimates of pure decision time (overall response time minus movement time in a simple reaction time task) revealed a difference between advanced and early PO patients. Advanced PO patients showed an overall slowing of decision time in the reaction time tasks, but the effect of the cognitive load of the tasks on the decision time was comparable to a control group. The untreated early PO patients performed quite normally in the more simple decision tasks but showed a disproportionate slowing of decision time in tasks with higher cognitive load. @ 1992 Academic Press. Inc
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