Skin Replacement Therapies for Diabetic Foot Ulcers: Systematic review and meta-analysis  

Oleh:

Blozik, Eva ; Scherer, Martin

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 31 no. 04 (Apr. 2008), page 693.

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K.2008.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Diabetic ulcer complications are a leading cause of hospitalization and amputation. Of the 20 million individuals with diabetes, 10-15% are at risk for developing diabetic ulcers. Standard therapy involves the use of dressings to protect the wound bed from trauma and to absorb exsudate; offloading high pressure from the wound bed, e.g., by prescribing protective footwear; and wound bed preparation to accelerate endogenous healing and facilitate the effectiveness of topically applied substances. But these measures are often deficient in healing all diabetic ulcers when the patient's own intrinsic wound-healing system is insufficient. In such patients, skin replacement therapies are second-line treatment options; however, the effectiveness of skin replacement therapies in treatment od diabetic ulcers is unclear. the objective of this study is to assess their effectiveness using evidence from randomized trials in diabetic leg and foot ulceration.

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