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ArtikelSingle-Molecule Cut-and-Paste Surface Assembly  
Oleh: Kufer, S.K. ; Puchner, E.M. ; Gumpp, H. ; Liedl, T. ; Gaub, H.E.
Jenis: Article from Bulletin/Magazine
Dalam koleksi: SCIENCE (keterangan: ada di Proquest) vol. 319 no. 5863 (Feb. 2008), page 594.
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: S01.K.2008.02
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
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Isi artikelWe introduce a method for the bottom-up assembly of biomolecular structures that combines the precision of the atomic force microscope (AFM) with the selectivity of DNA hybridization. Functional units coupled to DNA oligomers were picked up from a depot area by means of a complementary DNA strand bound to an AFM tip. These units were transferred to and deposited on a target area to create basic geometrical structures, assembled from units with different functions. Each of these cut-and-paste events was characterized by single-molecule force spectroscopy and single-molecule fluorescence microscopy. Transport and deposition of more than 5000 units were achieved, with less than 10% loss in transfer efficiency.
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