Oral Glucose Tolerance Test: A Reliable Tool for Early Detection of Glucose Abnormalities in Patients With Acute Myocardial Infarction in Clinical Practice : A report on repeated oral glucose tolerance tests from the GAMI Study  

Oleh:

Wallander, Marit ; Malmberg, Klas ; Norhammar, Anna ; Ryden, Lars ; Tenerz, Ake

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 31 no. 01 (Jan. 2008), page 36.
Topik: ADA; American Diabetes Association ; AMI; acute myocardial infarction ; EASD; European Association for the Study of Diabetes ; ESC; European Society of Cardiology ; GAMI; Glucose tolerance in Acute Myocardial Infarction ; HOMA-IR; homeostasis model assessment of insulin resistance ; IGI; insulinogenic index ; IGT; impaired glucose tolerance ; NGT; normal glucose tolerance ; OGTT; oral glucose tolerance test ; WHO; World Health Organization

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K.2008.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

OBJECTIVE—Previously undetected glucose abnormalities are common in patients with acute myocardial infarction (AMI). We evaluated long-term reliability of early glucometabolic classification of patients with AMI by repeated oral glucose tolerance tests (OGTTs). RESEARCH DESIGN AND METHODS—A glucometabolic OGTT-based classification was obtained in 122 patients by measuring capillary whole-blood glucose. The classification was performed on three occasions, before hospital discharge and 3 and 12 months thereafter. RESULTS—At discharge, 34, 31, and 34% were classified as having normal glucose tolerance, impaired glucose tolerance (IGT), or type 2 diabetes, respectively, and 93% of all patients with type 2 diabetes were still classified with type 2 diabetes (n = 27) or IGT (n = 12) after 12 months. The agreements between the OGTTs at discharge and 3 and 12 months were = 0.35, P < 0.001, and = 0.43, P < 0.001, respectively. CONCLUSIONS—The outcome of an OGTT performed in AMI patients at hospital discharge reliably informs on long-term glucometabolic state.

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