Lactation After Normal Pregnancy Is Not Associated With Blood Glucose Fluctuations  

Oleh:

Bentley-Lewis, Rhonda ; Goldfine, Allison B. ; Green, Dina E. ; Seely, Ellen W.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Diabetes Care vol. 30 no. 11 (Nov. 2007), page 2792.

Ketersediaan

Perpustakaan FK Nomor Panggil: D05.K.2007.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

We observed no significant glucose changes during the period before or after lactation in women who had pregnancies uncomplicated by pregestational or gestational diabetes. Moreover, these healthy women did not have differences in the mean glucose levels obtained prelactation compared with postlactation, nor did they manifest hypoglycemia in response to lactation. Our data extend the current literature on blood glucose response to lactation by examining healthy women. Data in type 1 diabetic women have revealed that breastfeeding lowered blood glucose concentrations and made achieving metabolic control more difficult (6). Studies have demonstrated that women with gestational diabetes benefit from lactation, manifesting improved glucose metabolism with a twofold increase in subsequent type 2 diabetes among nonlactating women (7). However, to our knowledge, there are no published data using CGMS to characterize glucose fluctuations in healthy lactating women. Our main study limitation is sample size. However, although only nine women were studied, each had CGMS data providing blood glucose sampling every 5 min both before and after lactation to understand blood glucose characteristics during this period. Additionally, the validity of our selected blood glucose analysis periods before and after lactation was dependent on participant reliability in documenting food intake. In conclusion, we observed no significant blood glucose fluctuations in response to lactation among healthy women with a normoglycemic pregnancy history. Therefore, these women do not need to increase caloric intake specifically before or during lactation to prevent hypoglycemia. This is noteworthy because limiting postpartum caloric intake will facilitate the loss of excess pregnancy weight, thereby reducing the risk of developing obesity. Nonetheless, women should be aware of recommendations regarding healthy caloric intake during breast feeding (8). Moreover, further studies of glucose fluctuations during lactation in larger numbers of normoglycemic and diabetic women are warranted.

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