Leukotrienes  

Oleh:

Peters-Golden, Marc ; Henderson, William R.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The New England Journal of Medicine (keterangan: ada di Proquest) vol. 357 no. 18 (Nov. 2007), page 1841.

Ketersediaan

Perpustakaan FK Nomor Panggil: N08.K.2007.06 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Leukotrienes ("leuko," from white blood cells; and "trienes," three conjugated double bonds) comprise a family of products of the 5-lipoxygenase pathway of arachidonic acid metabolism. The cysteinyl leukotrienes C4, D4, and E4 account for the biologic activity that was previously termed "slow-reacting substance of anaphylaxis," and the efficacy of antagonists to type 1 cysteinyl leukotriene receptor (CysLT1) in asthma validates the importance of cysteinyl leukotrienes and CysLT1 in this disease.1 This article reviews both established understanding and recent advances in our knowledge about leukotrienes. Synthesis of Leukotrienes The synthesis of leukotrienes from substrate arachidonic acid is initiated by 5-lipoxygenase in . . .

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali