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An 18-mo randomized trial of a low-glycemic-index diet and weight change in Brazilian women
Oleh:
Sichieri, Rosely
;
Moura, Anibal S.
;
Genelhu, Virginia
;
Hu, Frank
;
Willett, Walter C.
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The American Journal of Clinical Nutrition vol. 86 no. 03 (Sep. 2007)
,
page 707.
Topik:
Low-glycemic-index diet
;
weight change
;
Brazilian women
Ketersediaan
Perpustakaan FK
Nomor Panggil:
A07.K.2007.03
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
Background: Despite interest in the glycemic index diets as an approach to weight control, few long-term evaluations are available. Objective: The objective was to investigate the long-term effect of a low-glycemic-index (LGI) diet compared with that of a high-glycemic-index (HGI) diet; all other dietary components were equal. Design: After a 6-wk run-in, we randomly assigned 203 healthy women [body mass index (in kg/m2): 23–30] aged 25–45 y to an LGI or an HGI diet with a small energy restriction. The primary outcome measure was weight change at 18 mo. Secondary outcomes included hunger and fasting insulin and lipids. Results: Despite requiring a run-in and the use of multiple incentives, only 60% of the subjects completed the study. The difference in glycemic index between the diets was 35–40 units (40 compared with 79) during all 18 mo of follow-up, and the carbohydrate intake from energy remained at 60% in both groups. The LGI group had a slightly greater weight loss in the first 2 mo of follow-up (–0.72 compared with –0.31 kg), but after 12 mo of follow-up both groups began to regain weight. After 18 mo, the weight change was not significantly different (P = 0.93) between groups (LGI: –0.41 kg; HGI: –0.26 kg). A greater reduction was observed in the LGI diet group for triacylglycerol (difference = –16.4 mg/dL; P = 0.11) and VLDL cholesterol (difference = –3.7 mg/dL; P = 0.03). Conclusions: Long-term weight changes were not significantly different between the HGI and LGI diet groups; therefore, this study does not support a benefit of an LGI diet for weight control. Favorable changes in lipids confirmed previous results.
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