Adult coeliac disease  

Oleh:

Hopper, Andrew D ; Hadjivassiliou, Marios ; Butt, Sohail ; Sanders, David

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: British Medical Journal (keterangan: ada di Proquest) vol. 335 no. 7619 (Sep. 2007), page 558.
Topik: Clinical review

Ketersediaan

Perpustakaan FK Nomor Panggil: B16.K.2007.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Summary points • The prevalence of coeliac disease is 0.5-1% in international population studies • A combination of tissue transglutaminase antibody, endomysial antibody, and immunoglobulin A should be used for initial testing • Antibody negative coeliac disease with villous atrophy is now recognised • Treatment should involve a gluten-free diet, with support from a dietitian and a gastroenterologist The prevalence of coeliac disease is 0.5-1% in international population studies. The delay in diagnosis is reported to range from 4.5 years to 9.0 years.1 2 Patients may present on numerous occasions to both primary and secondary care without coeliac disease being considered.3 Currently, for every adult patient in whom the disease is diagnosed, eight cases are estimated to go undetected.4 What is coeliac disease and why is it more common now? Coeliac disease (or gluten sensitive enteropathy) is defined as a state of heightened immunological responsiveness to ingested gluten (from wheat, barley, or rye) in genetically susceptible individuals. Coeliac disease has historically been considered to . . .

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