Uji Aktivitas Antibakteri dan Sitotoksik Ekstrak Metanol Aglaia silvestris (M.Roemer) Merr.  

Oleh:

Praptiwi

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI
Dalam koleksi: Biota Jurnal Ilmiah Ilmu-ilmu Hayati vol. XII no. 1 (Feb. 2007), page 23-27.
Topik: Aglaia silvestris; growth inhibition area; cytotoxic activity.

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: BB74 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The bacterial and sitotoxic activities of ganggo (Aglaia silvestris (M.Roemer) Merr. methanol extract were determined in this study. Antibacterial in-vitri test of ganggo methanol extract was exposed to gram positive (Staohylococcus aureus ATCC 25923, Streptococcus agalactiae ATTC 8190, and Streptococcus sp.) and gram negative (Salmonella typhii NCTC 786 E, Aschericia coli ATCC 25922, and Pseudomonas pseudomallei ATCC 15682) bacteria. The extract concentrations were 50,25 and 12.5%, and done in triplicate. The growth inhibition area of extract was compared to those of standard antibiotic (10 unit ampicilin). Cytotoxic test of ganggo extract was done utilizing Brine Shrimp Lethality Test (BST) with Artemia salina. The result showed that growth inhibition area of 12,5% ganggo methanol extract to P. pseudomallei (19mm) was wider that that of 10 unit ampicilin (0 mm). It showed that P. pseudomallei was sensitive to ganggo methanol extract. The result of BST showed that LC50 of ganggo extract was 345,44 ppm. It was concluded that ganggo methanol extract had antibacterial effect on some bacteria isolates and had cytotoxic effects with LC50 345.44 ppm.

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