Detail Genes Required for Mitotic Spindle Assembly in Drosophila S2 Cells   Oleh:  Goshima, Gohta ; Wollman, Roy ; Goodwin, Sarah S ; Zhang, Nan ; Scholey, Jonathan M. ; Vale, Ronald D ; Stuurman, Nico Jenis: Article from Bulletin/Magazine Dalam koleksi: SCIENCE (keterangan: ada di Proquest) vol. 316 no. 5823 (Apr. 2007), page 417. Ketersediaan Perpustakaan FK Nomor Panggil: S01.K.2007.04 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada     Lihat Detail Induk Isi artikel The formation of a metaphase spindle, a bipolar microtubule array with centrally aligned chromosomes, is a prerequisite for the faithful segregation of a cell's genetic material. Using a full-genome RNA interference screen of Drosophila S2 cells, we identified about 200 genes that contribute to spindle assembly, more than half of which were unexpected. The screen, in combination with a variety of secondary assays, led to new insights into how spindle microtubules are generated; how centrosomes are positioned; and how centrioles, centrosomes, and kinetochores are assembled. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

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