Detail A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A   Oleh:  Kawaguchi, Riki ; Yu, Jiamei ; Honda, Jane ; Hu, Jane ; Legge, Julian White ; Ping, Peipei ; Wiita, Patrick ; Bok, Dean ; Sun, Hui Jenis: Article from Bulletin/Magazine Dalam koleksi: SCIENCE (keterangan: ada di Proquest) vol. 315 no. 5813 (Feb. 2007), page 820. Ketersediaan Perpustakaan FK Nomor Panggil: S01.K.2007.02 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada     Lihat Detail Induk Isi artikel Vitamin A has diverse biological functions. It is transported in the blood as a complex with retinol binding protein (RBP), but the molecular. mechanism by which vitamin A is absorbed by cells from the vitamin A-RBP complex is not clearly understood. We identified in bovine retinal pigment I epithelium cells STRA6, a multitransmembrane domain protein, as a specific membrane receptor for RBP. STRA6 binds to RBP with high affinity and has robust vitamin A uptake activity from the .. vitamin A-RBP complex. It is widely expressed in embryonic development and in adult organ systems. The RBP receptor represents a major physiological mediator of cellular vitamin A uptake. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Kembali

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