The Relationship Between a Model of End Stage Liver Disease Score (MELD Score) and The Occurrence of Spontaneous Bacterial Peritonitis in Liver Cirrhotic Patients  

Oleh:

Gayatri, A.A. Ayu Yuli ; Suryadharma, IGA ; Purwadi, N. ; Wibawa, I.D.N.

Jenis: Article from Journal - ilmiah nasional - terakreditasi DIKTI
Dalam koleksi: Acta Medica Indonesiana vol. 39 no. 02 (Apr. 2007), page 75.
Topik: SBp; MEW score; pattern of bacterial culture; antibiotic.

Ketersediaan

Perpustakaan FK Nomor Panggil: A02.K.2004.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

ABSTRACT Aim: to determine relationship between MEW score and the occurrence of SBp, prevalence of SBp, pattern of bacterial culture and antibiotic susceptibility of causative bacteria of liver cirrhotic patients at Sanglah Hospital. Methods: study design was a cross-sectional analytic study. The population in this study consists of liver cirrhotic patients admitted at Sanglah Hospital Denpasar from June 2005 to February 2006. Results: this result confirmed that the MEW score is a reliable index of disease severity & that higher MEW scores had a significantly more frequent SBP prevalence in patients with a MEW score of 18 or more compared with that in patients with a MEW score of 17 or less (p=O.Ol; 95% CI = 1.379-15.537). Prevalence of SBP was 30.6%. Thirteen patients (68.4%) had monomicrobial positive culture of Aerob bacteria, consisting of Gram negative bacterias in 10 (77%), wit~ Escherichia coli and Acinettobacter baumanii being the most frequent, and 3 (23%) had Gram positive bacteria. High sensitivity to Cefoperazone, Cefotaxim, Ceftazidime, Cefpirome, Ciprofloxacin, Fosfomicin, Meropenem, Streptomycin, Gentamycin, Trimethoprim/ Sulphamethoxazole, were shown. Conclusion: based on this study we concluded that severe liver cirrhosis with MEW score ~ 18 was associated with an increase risk of SBp, with a prevalence of 30.6%. Common causes of SBP mostly were Escherichia coli and Acinettobacter baumanii, which were sensitive to antibiotic treatment of Cefoperazone, Cefotaxime and Ciprofloxacin.

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