Preexisting Morbidity as an Independent Risk Factor for Perioperative Acute Thromboembolism Syndrome  

Oleh:

Kikura, Mutsuhito ; Takada, Tomosue ; Sato, Shigehito

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Archives of Surgery vol. 140 no. 12 (Dec. 2005), page 1210-1217.

Ketersediaan

Perpustakaan FK Nomor Panggil: A32.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Hypothesis Preexisting morbidities are risk factors for perioperative arterial or venous thromboembolic events and subsequent death within 30 postoperative days. Design Prospective cohort study. Setting University-affiliated general hospital. Patients A total of 21 903 surgery patients treated from January 1, 1991, through December 31, 2002. Main Outcome Measures Independent risk factors for perioperative arterial or venous thromboembolic events. Results History of atrial fibrillation and coronary artery disease increased the risk of myocardial infarction (odds ratio [95% confidence interval], 4.3 [2.8-6.7]). History of stroke increased the risk of stroke (2.4 [1.4-4.1]) and death (4.7 [1.3-17.3]). Diabetes mellitus increased the risk of myocardial infarction (2.1 [1.3-3.2]), and hyperuricemia increased the risk of stroke (3.5 [1.2-9.8]), and both increased the risk of death (4.3 [1.3-14.1] and 11.8 [2.2-63.5], respectively). History of myocardial infarction increased the risk of deep vein thrombosis (7.7 [1.7-34.7]). Cancer increased the risk of all thromboembolism (2.4 [1.9-3.2]). Trend analysis showed that preexisting morbidities will increase 1.5-fold and thromboembolic events will increase 3-fold during the next decade. Conclusion Cardiac and cerebrovascular diseases, metabolic diseases, and cancer are becoming increasingly high-risk comorbidities for perioperative acute thromboembolism syndrome.

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