Apoptosis: Morfologi dan Mekanisme  

Oleh:

Suryawinata, Kidyarto ; Murtono, Cyprianus

Jenis: Article from Journal - ilmiah nasional - tidak terakreditasi DIKTI - atma jaya
Dalam koleksi: Majalah Kedokteran Damianus vol. 06 no. 02 (May 2007), page 121-126.
Topik: Apoptosis; Morphology; Caspases
Fulltext: D01 v6 n2 p121 kelik2023.pdf (883.26KB)

Ketersediaan

Perpustakaan PKPM Nomor Panggil: M61 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada	Lihat Detail Induk
Perpustakaan FK Nomor Panggil: D01.K.2007.01 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada	Lihat Detail Induk

Isi artikel

Apoplosis, or programmed cell death, is defined by morphologic change in nonpathologic cell loss and is relevant to a wide spectrum of biology. Apoptosis is initiated by activation of CASPASES, Cystein Aspartyl-Specific Proteases, Which, on the other hand, can be activated by death receptor (extrinsic) and mitochondrial (intrinsic) pathway. Morphologically, apoptosis is characterized by cellular shrinking, chromatin condensation, cytoplasmic membrane blebbing and the released of small membrane bound apoptolic bodies, organdies and nuclear fragments are generally phagocytosed without causing an inflammatory response. Dysregulated apoptosis may contribute to a number of diseases such as cancer (in insufficient apoptosis.) and neurodegenerative disorders (in excessive apoptosis).

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