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ArtikelInfectious Complications in Solid Organ Transplant Recipients  
Oleh: Nicholson, Veronika ; Johnson, Philip C.
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Surgical Clinics of North America (Keterangan: ada di ClinicalKey) vol. 74 no. 5 (Okt. 1994), page 1223.
Isi artikelInfection and allograft rejection remain the major causes of morbidity and mortality in the solid organ transplant patient. The incidence of infectious complications has decreased with the use of prophylactic antibiotic agents and improved surgical techniques. Infections that occur post-transplantation vary in a predictable pattern depending on which organ is transplanted and the time course post-transplantation. The two most important factors that predispose transplant patients to infection are the use of cadaveric organs and repeated treatment of recurrent or persistent rejection. It is important to screen the donor and the recipient for possible infectious disease risks to prevent reactivation of latent infection and the transfer from the donor to recipient of infection, and to minimize intraoperative and nosocomial infections. Infectious disease complications require rapid diagnosis and early treatment for cure. Further evaluation is necessary into the development of more specific immunosuppressive agents, prophylactic antibiotic regimens, and antifungal agents.
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