Surgical Management of Children with Hemoglobinopathies  

Oleh:

Ware, Russell E. ; Filston, Howard C.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Surgical Clinics of North America (Keterangan: ada di ClinicalKey) vol. 72 no. 6 (Dec. 1992), page 1223.

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Perpustakaan FK Nomor Panggil: S08.K Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Careful preparation for anesthesia and operation is essential for patients with sickle hemoglobinopathy to reduce the hazard of inducing sickle crisis as a result of microvascular plugging by the sickle erythrocytes. Modern transfusion therapy administered over several weeks prior to the operation not only corrects the chronic anemia, but suppresses erythropoiesis of cells containing Hb S from the patient’s bone marrow, leaving a majority of cells containing hemoglobin A, and providing a “safety net” in case a sickle-inducing insult does occur.

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