Resistance to Antifungal Agents  

Oleh:

DeMuri, Gregory P. ; Hostetter, Margaret K.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 42 no. 03 (Jun. 1995), page 665.

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.1995.03 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Among immunocomprised hosts, invasive infections with Candida species, Cryptococcus neoformans, and Aspergillus have increased dramatically over the past decade. Normal patients are also susceptible to life-threatening infections with the dimorphic fungi Histoplas ma capsu latu in, Coccidioides immitis, Blastomyces derniatiditis, and Sporothrix schenkii. In these contexts, the widespread use of antifungal agents has been accompanied by the development of resistance among medically important fungi. This article reviews the mechanisms of action of the polyene amphotericin B, the triazoles fluconazole and itraconazole, and pyrimidine analog flucytosine. Shortcomings of present methods of susceptibility testing for medically important fungi will be discussed, and clinical reports of resistance to these antifungal agents will be reviewed. A reasonable assessment of the scope of resistance to antifungal agents is provided.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali