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ArtikelHuman Papillomavirus Infection in Adolescents  
Oleh: Moscicki, Anna-Barbara
Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 46 no. 04 (Aug. 1999), page 783-808.
Topik: The Sexually Active Adolescent
Ketersediaan
  • Perpustakaan FK
    • Nomor Panggil: P13.K.1999.04
    • Non-tandon: 1 (dapat dipinjam: 0)
    • Tandon: tidak ada
    Lihat Detail Induk
Isi artikelHuman papillomavirus (HPV)-include lesions span a wide clinical spectrum from benign lesions to precancerous lesions, with only a minority of infections resulting in invasive cancers. Unfortunately, the prevalence of HPV infection is so widespread that the incidence of low- and high-grade squamous intra-epithelial lesions (HSIL) has doubled in the last decade resulting in large societal and personal costs. The recent gain in knowledge of HPVs genomic function has led to a greater understanding of the natural history of HPV infection in women starting from infection to the development of invasive cancer. It is now clear that LSIL is a benign HPV-associated lesion and could best be observed in young women. On the other hand, HPV infections during adolescence appear to be a risk for the future development of HSIL and invasive cancers supporting the need for close surveillance in women who initiated intercourse at a young age. Last, new self-applied therapies show promise in adolescents but their use in the age group requires closer evaluation.
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