Stem-Cell Transplantation for Inherited Immunodeficiency Disorders  

Oleh:

Horwitz, Mitchell E.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 47 no. 06 (Dec. 2000), page 1371-1388.
Topik: Primary Immune Deficiencies (Presentation; Diagnosis; Management)

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.2000.06 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

For many congenital immunodeficiency disorders, stem-cell transplantation is curative. The decision to proceed with this potentially dangerous treatment depends on the severity of the underlying illness. This article discusses the mechanics of allogeneic stem-cell transplantation and the clinical experience to date in the treatment of immunodeficiency disorders. The recent advent of nonmyeloablative, stem-cell transplantation also is presented in the context of clinical trials examining the efficacy of this less-toxic approach to stem-cell replacement for immunodeficiency disorders.

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