Detail Food for Thought: Fluctuations in Brain Extracellular Glucose Provide Insight Into the Mechanisms of Memory Modulation Bibliografi Author: McNay, Ewan C. ; Gold, Paul E. (Co-Author) Topik: brain; cognition; energy demand; extracellular; glucose; hippocampus; learning; memory; neural metabolism Bahasa: (EN )     Penerbit: SAGE Publications     Tempat Terbit: London    Tahun Terbit: 2002     Jenis: Article - untuk jurnal ilmiah Fulltext: 264BCNR14.pdf (156.0KB; 0 download) Abstract Extensive evidence indicates that peripheral or direct central glucose administration enhances cognitive processes in rodents and humans. These behavioral findings suggest that glucose acts directly on the brain to regulate neural processing, a function that seems incompatible with the traditional view that brain glucose levels are high and invariant except under extreme conditions. However, recent data suggest that the glucose levels of the brain?s extracellular fluid are lower and more variable than previously supposed. In particular, the level of glucose in the extracellular fluid of a given brain area decreases substantially when a rat is performing a memory task for which the brain area is necessary. Together with results identifying downstream effects of such variance in glucose availability, the evidence leads to new thinking about glucose regulation of brain functions including memory. Opini Anda Klik untuk menuliskan opini Anda tentang koleksi ini! Lihat Sejarah Pengadaan  Konversi Metadata   Kembali

Copyright © 2006, 2007 Unika Atma Jaya, all rights reserved