Cell-Level Finite Element Studies of Viscous Cells in Planar Aggregates  

Oleh:

Brodland, G. Wayne ; Helen H. Chen

Jenis: Article from Bulletin/Magazine
Dalam koleksi: Journal of Biomechanical Engineering vol. 122 no. 4 (2000), page 394-401.
Topik: cells; cell - level; finite element; viscous cells; planar aggregates

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: JJ52.2 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

A new cell - level finite element formulation is presented and used to investigate how epithelia and other planar collections of viscous cells might deform during events such as embryo morphogenesis and wound healing. Forces arising from cytoskeletal components, cytoplasm viscosity, and cell - cell adhesions are included. Individual cells are modeled using multiple finite elements, and cell rearrangements can occur. Simulations of cell - sheet stretching indicate that the initial stages of sheet stretching are characterized by changes in cell shape, while subsequent stages are governed by cell rearrangement. Inferences can be made from the simulations about the forces that act in real cell sheets when suitable experimental data are available.

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali