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Hemolytic Potential of Hydrodynamic Cavitation
Oleh:
Bartlett, Robert H.
;
Chambers, Sean D.
;
Ceccio, Steven L.
Jenis:
Article from Bulletin/Magazine
Dalam koleksi:
Journal of Biomechanical Engineering vol. 122 no. 4 (2000)
,
page 321-326.
Topik:
potential flow theory
;
hemolytic
;
hydrodynamic
;
cavitation
Ketersediaan
Perpustakaan Pusat (Semanggi)
Nomor Panggil:
JJ52.2
Non-tandon:
1 (dapat dipinjam: 0)
Tandon:
tidak ada
Lihat Detail Induk
Isi artikel
The purpose of this study was to determine the hemolytic potentials of discrete bubble cavitation and attached cavitation. To generate controlled cavitation events, a venturi - geometry hydrodynamic device, called a Cavitation Susceptibility Meter (CSM), was constructed. A comparison between the hemolytic potential of discrete bubble cavitation and attached cavitation was investigated with a single - pass flow apparatus and a recirculating flow apparatus, both utilizing the CSM. An analytical model, based on spherical bubble dynamics, was developed for predicting the hemolysis caused by discrete bubble cavitation. Experimentally, discrete bubble cavitation did not correlate with a measurable increase in plasma - free hemoglobin (PFHb), as predicted by the analytical model. However, attached cavitation did result in significant PFHb generation. The rate of PFHb generation scaled inversely with the Cavitation number at a constant flow rate, suggesting that the size of the attached cavity was the dominant hemolytic factor.
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