The Molecular Basis of pediatric Hypertension  

Oleh:

Ingelfinger, Julie R

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Pediatric Clinics of North America vol. 53 no. 05 (Oct. 2006), page 1011.

Ketersediaan

Perpustakaan FK Nomor Panggil: P13.K.2006.05 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

Blood pressure, the product of cardiac output and peripheral vascular resistance, follows a circadian rhythm and is altered by a host of circulating and local substances and by many physiologic events. The number of genes, signaling pathways, and systems involved in blood pressure regulation is enormous, and dissecting those factors that are most important in hypertension has proven challenging. This article discusses molecular mechanisms of hypertension in several conditions in which mutations in a single gene give rise to hypertension and then considers the contribution of these and other genes to essential hypertension.

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