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Neuroenergetics: Calling upon Astrocytes to Satisfy Hungry Neurons
Oleh:
Pellerin, Luc
;
Magistretti, Pierre J.
Jenis:
Article from Journal - ilmiah internasional
Dalam koleksi:
The Neuroscientist vol. 10 no. 1 (Feb. 2004)
,
page 53–62.
Topik:
Glucose
;
Lactate
;
Monocarboxylate transporters
;
Aerobic glycolysis
;
Brain energy metabolism
Fulltext:
53TN101.pdf
(183.33KB)
Isi artikel
Classical neuroenergetics states that glucose is the exclusive energy substrate of brain cells and its full oxidation provides all the necessary energy to support brain function. Recent data have revealed a more intricate picture in which astrocytes play a key role in supplying lactate as an additional energy substrate in register with glutamatergic activity.
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