Glutamate and the Presynaptic Control of Spinal Sensory Transmission  

Oleh:

Huettner, James E. ; Kerchner, Geoffrey A. ; Min, Zhuo

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Neuroscientist vol. 8 no. 2 (Apr. 2002), page 89–92.
Topik: Pain; Transmitter release; Dorsal root ganglia
Fulltext: 89TN82.pdf (55.36KB)

Isi artikel

Sensory neurons, in particular the small- and medium-diameter cells that sense painful stimuli, express both ionotropic and metabotropic glutamate receptors, which may regulate transmission between sensory neurons and their targets in the spinal cord dorsal horn. Although the roles that these receptors play in normal physiology are not completely understood, recent work has provided strong evidence for their ability to modulate transmitter release from primary afferent terminals.

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