Neuregulins and the Shaping of Synapses  

Oleh:

Ozaki, Miwako

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: The Neuroscientist vol. 7 no. 2 (Apr. 2001), page 146–154.
Topik: Neuregulin; ErbB; NMDA receptor; GABAA receptor; Synapse; Activity-dependent
Fulltext: 146TN72.pdf (2.56MB)

Isi artikel

In developing and mature neural circuits, neural electrical activity controls the correct formation of connections and their state. Neuregulins (NRGs) mediate between the electrical neural activity and molecular components by regulating the expression of ion channel receptors or transmitter release in synapses. Furthermore, NRGs may be signaling factors involved in tuning locomotion or other higher functions by coordinating excitatory and inhibitory neurons.

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