Engineering Vascularized Tissue  

Oleh:

Jain, Rakesh K. ; Au, Patrick ; Tam, Josh ; Duda, Dan G. ; Fukumura, Dai

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Nature Biotechnology: The Science and Business of Biotechnology vol. 23 no. 7 (Jul. 2005), page 821-822.
Topik: TISSUES; engineering; vascularized; tissue

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: NN9.3 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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Isi artikel

The creation in vitro of vascularized skeletal muscle represents a first step to the engineering of more complex tissue architectures. If tissue engineering is ever to surpass the tissue thickness limit of 100 - 200 um, it must overcome the challenge of creating functional blood vessels to supply cells with oxygen and nutrients and to remove waste products. One possible solution is vascularization of engineered tissue constructs before transplantation. In this issue, levenberg et al, demonstrate the potential of such an approach by engineering three dimensional vascularized skeletal muscle constructs from myoblasts, fibroblasts and endothelial cells.

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