Editing The Message from A to I  

Oleh:

Nishikura, Kazuko

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Nature Biotechnology: The Science and Business of Biotechnology vol. 22 no. 8 (Agu. 2004), page 962-963.
Topik: rna; edit message; RNA

Ketersediaan

Perpustakaan Pusat (Semanggi) Nomor Panggil: NN9.1 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

Lihat Detail Induk

Isi artikel

Numerous adenosine to inosine editing sites found in mRNA sequences raise new questions about the biological significance of RNA editing. RNA editing is a process that results in the synthesis of proteins that are not directly encoded in the genome. One type of RNA editing involves the conversion of adenosine (A) residues into inosine (1) residues through an action of ADAR (adenosine deaminases acting on RNA). When functioning improperly, this essential process in mammalian development can give rise to pathological conditions ranging from epilepsy to malignant gliomas. Identification of most editing sites has been serendipitous, discovered during comparison of cDNA sequences to corresponding genomic sequences...

Opini Anda

Klik untuk menuliskan opini Anda tentang koleksi ini!

Kembali