Converging Evidence for Brain Stem Injuiry in Autism  

Oleh:

Rodier, Patricia M.

Jenis: Article from Journal - ilmiah internasional
Dalam koleksi: Development and Psychopathology vol. 14 no. 3 (2002), page 537-558.
Topik: BRAIN; autism; converging evidence; brain stem injury
Fulltext: 537.pdf (213.19KB)

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Perpustakaan Pusat (Semanggi) Nomor Panggil: DD21.4 Non-tandon: 1 (dapat dipinjam: 0) Tandon: tidak ada

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The hypothesis that brain stem injury plays a role in the autism spectrum disorders was suggested by evidence that exposure to thalidomide during the earliest stages of brain development increases the risk of autism spectrum disorders. The implications for the embryological origin of autism first led to studies of neuroanatomy in a human case and an animal model and then to examinations of minor craniofacial features in autism. But the general hypothesis had much broader implications. It has now generated studies of the behavioural and neurological symptoms of human patients, of human molecular genetics and population genetics, and of animal behavioural teratology and molecular pharmacology. The collection of this range of data was made possible by adding experts from many fields to the research team. They worked both independently and collaboratively to try to unravel the etiology of autism.

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